HOMOGENIZERS

Homogenization & Emulsification

Homogenization or homogenization is any of several processes used to make a mixture of two mutually insoluble liquids the same throughout. This is achieved by turning one of the liquids into a state consisting of extremely small particles distributed uniformly throughout the other liquid.

Our partner, Kinematica, has a wide range of products for the purpose of homogenization and emulsification offering Quality without compromises, in-depth expertise, and continuous innovation. Attention to details, transparency, and a genuine consultancy approach allows APICAL & Kinematica to offer tailor-made solutions for every application – even the most difficult ones.  

The legendary POLYTRON® brand that is encompassing the line of Rotor/Stator technology Homogenizers Disperse and homogenize for batch processing in laboratories, pilots plants, and production.

We also offer powerful Stirring and Dry Milling solutions under the POLYMIX® brand. If you’re looking for highly-customizable reactors they can be found under the REACTRON® brand.

Manufacturers we trust

Kinematica is the preferred manufacture for Apical when it comes to homogenization & emulsification. They have a long track record of success and we’re happy to be a direct OEM. For a list of products available or just more information on specific units, click the link below.

A1-Kinematica Homogenizing Solutions

Since 1962, Kinematica has provided cutting edge rotor-stator, membrane and high-pressure homogenization throughout pharma, chemicals, cosmetics, food & life science.

Apical and Kinematica solutions are backed by in-depth expertise, continuous innovation, transparency and consultancy that is genuine and focused on the success of your business.

Development Applications Overview:

Emulsions for Eye Drops

Food & Aromatic Sciences

Batch Immersion Mixing

Water-Soluble Ingredient Development

Liquid Oral Suspensions

Vaccine & Ampoule Solutions

ECG Gels

Suppositories

Wet Milling

Inline Mixing & Flow Chemistry

Clear Dispersions

Natural-Based Pharmaceuticals

Micro & Lipo-Encapsulations

Tablet Coatings

Ointments & Creams

Pharmaceutical Crystallizations

Cough Syrup

Tableting

Etc.

Apical has taken years of validated field experience and product trials to develop practical technologies that work every day. We combine academic principles with cutting-edge design to provide equipment that can be relied on for years to come with safe, easy operation, high throughputs and consistent product. The same can certainly be said for Kinematica AG.


Together, we work to master the finer points,and deliver high throughputs, successful process development, facility safety and efficient commercialization.


Systems are built to DIN and cGMP standards for consistent production as well OSHA guidelines for safety. Apical takes industry guidelines seriously to ensure limited downtime, straight-forward audits and predictable operation.

No myths about residence time, degradation or physics, no designs with built-in obsolescence, no exaggerations about system capabilities or pay-to-play obstacles to efficient processing.

Apical has tested a wide range of designs under production settings to pierce the veil and remove the mystique around chemical processing so business operators can focus on the customer and not a daily headache.

Apical - Kinematica solutions can include:


REACTRON®

Multi-purpose highly scalable reactors - Customized, turn-key reactor systems for research, development, formulation testing, and pre-production assessment.

MEGATRON®

In-line dispersers - Multi-stage dispersing and homogenizing equipment for continuous and / or recirculating processing in production or pilot plants.

POLYMIX®

Multi-purpose stirring and milling systems - Sample preparation equipment range for high performance fluids mixing, dispersing, and wet / dry milling.

MICROTRON®

Bottom-mounted homogenizers & blenders - High-performance systems for effective blending and bottom-up batch homogenizing of cuttable materials.

POLYTRON®

Immersion dispersers - Dispersing and homogenizing equipment for batch processing in laboratories, pilots plants, and production.

BIOTRONA®

Highly turbulent dynamic immersion mixers - High-performance mixing / stirring systems for medium to high viscosity fluids and highly solid content.

Apical also provides:


Installation Manual

SDS Sheets

Installation of Complete Systems

Training for Complete Systems

SOP for Operation

On-Going Technical Support


Batch Capacity

500mL to >100,000mL


Optimized Capacity

80% Total Volume


Typical Start-Up Time

5 Minutes


Typical Batch Runtime

10 to 30 Minutes

Apical-Kinematica homogenizing system features include:

  • Added turbulence increases efficiency of the recirculator, balances temperature throughout the condenser to improve condenser capacity and is vacuum-insulated to prevent touch burns.

  • Fitted for deep-vacuum, durability and easy assembly/disassembly, these junctures are fitted with PTFE centering rings & composite clamps.

  • German-made components known for consistency and longevity.

  • Principle glassware is meant to be permanently installed on the lattice, frame or skid to reduce breakage and increase safety.

  • Reflux of common solvents keeps systems looking and performing brand new for years to come.

  • Small & large vessels and be fitted with lifting systems, allowing for easy cleaning, maintenance and swapping of process vessels.

  • Ingredients & product can be continuously fed to the process or ejected from the system on to storage or packaging.

  • More than 80 dispersing aggregates with proprietary geometries.

  • Such as 316L (standard), Inconel, Hastelloy, Titan, SuperDuplex.

  • Homogenizing with industry-leading shear rates of up to 300,000 s-1 and tips speeds of up to 65m/s.

  • Including comprehensive certification in accordance with industry acknowledged standards for the highest class clean-room for complete sterile environments and zero-contamination.

Systems are designed & built to DIN standards.

Glassware meets ASTM specifications and is sourced from Kimble Kimax or Schott Duran Glass.

System electronics meet CSA, CE, UL, NRTL/OSHA standards & certifications.

All ancillary equipment is covered under manufacturer warranties of 1 year or longer. And, our systems can be built to accommodate electrical voltages around the globe.